Here are a few podcasts worth checking out.

News deconstruction.  Legislation analysis.  Media assassination.
The best podcast in the universe.
No Agenda with Adam Curry and John C. Dvorak.

The creators of the web series Yacht Rock bring you top ten lists of arbitrary music genres. Serious music nerds only.
Beyond Yacht Rock.

Eddie Trunk interviews the great artists from the world of hard rock and heavy metal.
Eddie Trunk.
Relive the music, movies, and culture of the greatest decade ever.
Stuck In The 80s with Steve Spears.

Marc Maron interviews fellow comedians while sharing his own inner demons.